CD6 anticorps (AA 133-608)

N° du produit ABIN7599974

Cet anticorps Lapin Polyclonal détecte spécifiquement CD6 dans FACS, WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour CD6 anticorps (AA 133-608) (ABIN7599974)

Antigène: CD6

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD6 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA

Détail du produit anti-CD6 anticorps

Épitope: AA 133-608

Fonction: Anti-T12/CD6 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-T12/CD6 Antibody Picoband® (ABIN7599974). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human T12/CD6 recombinant protein (Position: E133-Q608).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Aruffo, A., Melnick, M. B., Linsley, P. S., Seed, B. The lymphocyte glycoprotein CD6 contains a repeated domain structure characteristic of a new family of cell surface and secreted proteins. J. Exp. Med. 174: 949-952, 1991. 2. Bowen, M. A., Whitney, G. S., Neubauer, M., Starling, G. C., Palmer, D., Zhang, J., Nowak, N. J., Shows, T. B., Aruffo, A. Structure and chromosomal location of the human CD6 gene. J. Immun. 158: 1149-1156, 1997. 3. De Jager, P. L., Jia, X., Wang, J., de Bakker, P. I. W., Ottoboni, L., Aggarwal, N. T., Picco, L., Raychaudhuri, S., Tran, D., Aubin, C., Briskin, R., Romano, S., and 22 others. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nature Genet. 41: 776-782, 2009.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur CD6

Antigène: CD6

Autre désignation: CD6

Sujet:

Synonyms: Fructose-bisphosphate aldolase B, Liver-type aldolase, ALDOB, ALDB

Tissue Specificity: Pancreas-specific (at protein level). Loss of expression is seen in ductal type pancreas cancers.

Background: CD6 (Cluster of Differentiation 6) is a human protein encoded by the CD6 gene. This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 135 kDa

ID gène: 923

UniProt: P30203